Basic Laboratory Research

Analgesic Effects of Acupuncture

1.            Han JS, Tang J, Ren MF, Zhou ZF, Fan SG, Qiu XC. Central neurotransmitters and acupuncture analgesia. The American journal of Chinese medicine. Winter 1980;8(4):331-348.

2.            Zou G, Yi QC, Wu SX, et al. Enkephalin involvement in acupuncture analgesia-radioimmunoassay. Scientia Sinica. Sep 1980;23(9):1197-1207.

3.            Han JS, Terenius L. Neurochemical basis of acupuncture analgesia. Annual review of pharmacology and toxicology. 1982;22:193-220.

4.            Lewith GT, Kenyon JN. Physiological and psychological explanations for the mechanism of acupuncture as a treatment for chronic pain. Social science & medicine. 1984;19(12):1367-1378.

5.            Zhu LX, Shi QY. Activation of nucleus raphe magnus by acupuncture and enkephalinergic mechanism. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine. Jun 1984;4(2):111-118.

6.            Yang MM, Kwok JS. Evaluation on the treatment of morphine addiction by acupuncture Chinese herbs and opioid peptides. The American journal of Chinese medicine. 1986;14(1-2):46-50.

7.            Takeshige C, Luo CP, Hishida F, Igarashi O. Differentiation of acupuncture and nonacupuncture points by difference of associated opioids in the spinal cord in production of analgesia by acupuncture and nonacupuncture point stimulation, and relations between sodium and those opioids. Acupuncture & electro-therapeutics research. 1990;15(3-4):193-209.

8.            Guoxi T. The action of the visceronociceptive neurons in the posterior group of thalamic nuclei: possible mechanism of acupuncture analgesia on visceral pain. The Kitasato archives of experimental medicine. Apr 1991;64(1):43-55.

9.            Takeshige C, Tsuchiya M, Guo SY, Sato T. Dopaminergic transmission in the hypothalamic arcuate nucleus to produce acupuncture analgesia in correlation with the pituitary gland. Brain research bulletin. Jan 1991;26(1):113-122.

10.          Takeshige C, Nakamura A, Asamoto S, Arai T. Positive feedback action of pituitary beta-endorphin on acupuncture analgesia afferent pathway. Brain research bulletin. Jul 1992;29(1):37-44.

11.          Wu D. Mechanism of acupuncture in suppressing epileptic seizures. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine. Sep 1992;12(3):187-192.

12.          Andersson S, Lundeberg T. Acupuncture–from empiricism to science: functional background to acupuncture effects in pain and disease. Medical hypotheses. Sep 1995;45(3):271-281.

13.          Zhou L, Wu GC, Cao XD. Role of opioid peptides of rat’s nucleus reticularis paragigantocellularis lateralis (RPGL) in acupuncture analgesia. Acupuncture & electro-therapeutics research. Apr-Jul 1995;20(2):89-100.

14.          Ng LK. Auricular acupuncture in animals: effects of opiate withdrawal and involvement of endorphins. Journal of alternative and complementary medicine. Spring 1996;2(1):61-63; discussion 73-65.

15.          Chen BY. Acupuncture normalizes dysfunction of hypothalamic-pituitary-ovarian axis. Acupuncture & electro-therapeutics research. 1997;22(2):97-108.

16.          Shen J. Research on the neurophysiological mechanisms of acupuncture: review of selected studies and methodological issues. Journal of alternative and complementary medicine. 2001;7 Suppl 1:S121-127.

17.          Yang J, Liu WY, Song CY, Lin BC. Only arginine vasopressin, not oxytocin and endogenous opiate peptides, in hypothalamic paraventricular nucleus play a role in acupuncture analgesia in the rat. Brain research bulletin. Feb 15 2006;68(6):453-458.

Somatosensory Response by Acupuncture

1.            Budgell B, Sato A, Suzuki A, Uchida S. Responses of adrenal function to stimulation of lumbar and thoracic interspinous tissues in the rat. Neuroscience research. May 1997;28(1):33-40.

2.            Hotta H, Sato A, Sato Y, Uchida S. Stimulation of saphenous afferent nerve produces vasodilatation of the vasa nervorum via an axon reflex-like mechanism in the sciatic nerve of anesthetized rats. Neuroscience research. Feb 1996;24(3):305-308.

3.            Noguchi E, Ohsawa H, Kobayashi S, Shimura M, Uchida S, Sato Y. The effect of electro-acupuncture stimulation on the muscle blood flow of the hindlimb in anesthetized rats. Journal of the autonomic nervous system. Feb 15 1999;75(2-3):78-86.

4.            Sato A, Sato Y, Suzuki A, Uchida S. Neural mechanisms of the reflex inhibition and excitation of gastric motility elicited by acupuncture-like stimulation in anesthetized rats. Neuroscience research. Oct 1993;18(1):53-62.

5.            Sato A, Sato Y, Suzuki A, Uchida S. Reflex modulation of catecholamine secretion and adrenal sympathetic nerve activity by acupuncture-like stimulation in anesthetized rat. The Japanese journal of physiology. Oct 1996;46(5):411-421.

6.            Sato A, Sato Y, Uchida S. Blood flow in the sciatic nerve is regulated by vasoconstrictive and vasodilative nerve fibers originating from the ventral and dorsal roots of the spinal nerves. Neuroscience research. Dec 1994;21(2):125-133.

7.            Sato A, Sato Y, Uchida S. Regulation of regional cerebral blood flow by cholinergic fibers originating in the basal forebrain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. Jun 2001;19(3):327-337.

8.           Sato A, Sato Y, Uchida S. Regulation of cerebral cortical blood flow by the basal forebrain cholinergic fibers and aging. Autonomic neuroscience : basic & clinical. Feb 28 2002;96(1):13-19.

9.            Sato A, Sato Y, Uchida S. Activation of the intracerebral cholinergic nerve fibers originating in the basal forebrain increases regional cerebral blood flow in the rat’s cortex and hippocampus. Neuroscience letters. May 6 2004;361(1-3):90-93.

10.          Uchida S, Kagitani F, Nakayama H, Sato A. Effect of stimulation of nicotinic cholinergic receptors on cortical cerebral blood flow and changes in the effect during aging in anesthetized rats. Neuroscience letters. Jun 13 1997;228(3):203-206.

11.          Uchida S, Suzuki A, Hotta H, Sato A. The effects of morphine on supraspinal and propriospinal somatocardiac reflexes in anesthetized rats. Neuroscience letters. Jul 16 1999;269(3):161-164.